Preimplantation genetic testing legislation and accessibility in the Nordic countries
| Autor: | Kersti Lundin, Christel Hydén-Granskog, Julius Hreinsson, Hans Jakob Ingerslev, Jon Hausken, Snorri Einarsson, Erik Iwarsson, Marie Louise Grøndahl |
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| Přispěvatelé: | HUS Helsinki and Uusimaa Hospital District, Clinicum |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Economic growth aneuploidies Legislation in ART Reproductive medicine Legislation Harmonization Scandinavian and Nordic Countries DIAGNOSIS monogenic disorders Health Services Accessibility legislation in assisted reproductive technologies 03 medical and health sciences AGE 0302 clinical medicine 3123 Gynaecology and paediatrics Pregnancy Surveys and Questionnaires medicine Humans Genetic Testing 030212 general & internal medicine Preimplantation Diagnosis Genetic testing PGT legislation Gene Rearrangement assisted reproductive technologies 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Genetic Diseases Inborn Obstetrics and Gynecology Treatment options DNA General Medicine Aneuploidy preimplantation genetic testing legislation 3. Good health Nordic structural rearrangements population characteristics Female preimplantation genetic testing business |
| Zdroj: | Hreinsson, J, Lundin, K, Iwarsson, E, Hausken, J, Einarsson, S, Grøndahl, M L, Hydén-Granskog, C & Ingerslev, H J 2020, ' Preimplantation genetic testing legislation and accessibility in the Nordic countries ', Acta Obstetricia et Gynecologica Scandinavica, vol. 99, no. 6, pp. 716-721 . https://doi.org/10.1111/aogs.13831 |
| ISSN: | 1600-0412 0001-6349 |
| Popis: | Introduction Assisted Reproduction Technologies are in rapid development and implementation of preimplantation genetic testing (PGT) has allowed patients with genetic disorders to initiate pregnancies while minimizing or eliminating the risk of transmitting these disorders to their offspring. Testing for numeric chromosomal anomalies has been proposed as a way to increase efficacy in assisted reproduction, however this remains disputed. Legislation is lagging behind the rapid developments in this field. Material and methods We conducted a structured online survey of legislation and accessibility to Preimplantation Genetic Testing in the Nordic countries to compare the regulation and uptake of this technique. The survey was designed and answered by the authors. Results Key elements in regulation of preimplantation testing for monogenic disorders and structural rearrangements are similar in the Nordic countries although accessibility varies since only Denmark, Finland and Sweden have national clinics offering treatment. In addition, Denmark and Finland have private clinics offering PGT. Regulation is most stringent in Norway where a national board evaluates all couples seeking treatment. Treatment volumes vary between the Nordic countries with Norway and Finland having lowest treatment numbers. Preimplantation genetic testing for aneuploidy in the embryo varies between the Nordic countries where Finland and Iceland are allowed to offer this form of treatment, Denmark and Sweden only in the form of a research protocol while this form of testing is not allowed at all in Norway. Therefore the number of treatment cycles involving testing for embryo aneuploidy are lower in the Nordic countries compared to other countries where this treatment option is more common. Conclusions Science needs to inform politics regarding the rapidly evolving field of reproductive medicine and we recommend harmonization of legislation and accessibility between the Nordic countries. |
| Databáze: | OpenAIRE |
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