Altered Calcium Homeostasis in Adults with Cystic Fibrosis
| Autor: | Robert M. Aris, S. Dingman, David A. Ontjes, Gayle E. Lester |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Pancreatic disease Adolescent Cystic Fibrosis Endocrinology Diabetes and Metabolism chemistry.chemical_element Parathyroid hormone Calcium Excretion Calcitriol Bone Density Internal medicine medicine Vitamin D and neurology Humans Vitamin D Calcium metabolism Bone mineral business.industry medicine.disease Endocrinology chemistry Dietary Supplements Female Secondary hyperparathyroidism business |
| Zdroj: | Osteoporosis International. 10:102-108 |
| ISSN: | 1433-2965 0937-941X |
| Popis: | Bone mineral density (BMD) in cystic fibrosis (CF) patients falls progressively below normal with advancing age, in part due to steroid administration, low levels of sex hormones, chronic inflammatory disease, physical inactivity, and chronic malabsorption of calcium and/or vitamin D. The purpose of this study was to compare the fractional absorption of (45)Ca and urinary excretion of calcium in CF subjects and normal controls following a high-calcium breakfast containing (45)Ca. Seven young men and 5 young women with CF with pancreatic insufficiency were studied on two separate occasions, with and without administration of pancreatic enzymes. Eleven healthy young adults with normal BMD measurements served as controls. Mean T-scores at the lumbar spine and femur were significantly lower in the CF subjects (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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