Clinicopathological characteristics of early onset colorectal cancer
| Autor: | Fanny E. R. Vuik, Stella A.V. Nieuwenburg, Iris D. Nagtegaal, Manon C.W. Spaander, Ernst J. Kuipers |
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| Přispěvatelé: | Gastroenterology & Hepatology |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Colorectal cancer Gastroenterology Young Adult SDG 3 - Good Health and Well-being Internal medicine medicine Overall survival Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14] Humans Pharmacology (medical) In patient Lymph node Neoplasm Staging Early onset Hepatology Rectal Neoplasms business.industry Incidence Incidence (epidemiology) Poorly differentiated Middle Aged medicine.disease medicine.anatomical_structure Child Preschool Female Age of onset Colorectal Neoplasms business Carcinoma Signet Ring Cell |
| Zdroj: | Alimentary Pharmacology & Therapeutics, 54, 11-12, pp. 1463-1471 Alimentary Pharmacology and Therapeutics, 54(11-12), 1463-1471. Wiley-Blackwell Publishing Ltd Alimentary Pharmacology & Therapeutics, 54, 1463-1471 |
| ISSN: | 0269-2813 |
| Popis: | Contains fulltext : 245161.pdf (Publisher’s version ) (Open Access) BACKGROUND: The rising incidence of early onset colorectal cancer (EOCRC) might reflect a novel tumour entity. AIMS: To evaluate clinicopathological characteristics of sporadic EOCRC (in patients < 50 years old) and investigate changes over time METHODS: All patients with sporadic EOCRC between 1989 and 2016 were included and divided by age: 20-29 years (group I), 30-39 years (group II) and 40-49 years (group III). RESULTS: We included 6400 patients. The presence of signet-ring cells and more poorly differentiated tumours were more common in the younger age groups: 5.4% and 3.7% for signet-ring cells in group I and II vs 1.4% in group III (P 2005, P = 0.09), and a higher percentage of rectal cancer was found in age group III (34.3% 2005, P |
| Databáze: | OpenAIRE |
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