Squamous cell carcinoma arising in a case of vulvitis granulomatosa or vulval variant of Melkersson-Rosenthal syndrome
| Autor: | B. Hill, Strutton Gm, R. G. Wright, Hemamali Samaratunga |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Systemic disease animal structures Vulvitis Virus Vulva Melkersson–Rosenthal syndrome medicine Carcinoma Humans Lupus Erythematosus Systemic Papillomaviridae Cervix Lupus erythematosus Melkersson-Rosenthal Syndrome Vulvar Neoplasms urogenital system business.industry Nucleic Acid Hybridization Obstetrics and Gynecology DNA Neoplasm medicine.disease female genital diseases and pregnancy complications Tumor Virus Infections stomatognathic diseases medicine.anatomical_structure Oncology Carcinoma Squamous Cell Female medicine.symptom business |
| Zdroj: | Gynecologic Oncology. 41:263-269 |
| ISSN: | 0090-8258 |
| DOI: | 10.1016/0090-8258(91)90321-u |
| Popis: | A case of vulvitis granulomatosa or the vulval variant of Melkersson-Rosenthal syndrome (MRS) in a young adult patient with systemic lupus erythematosus is presented. She also had evidence of cervicovulvovaginal human papilloma virus (HPV) infection. Nine years later she developed a squamous cell carcinoma (SCC) of the vulva. HPV 6/11 was found by DNA in situ hybridization within a vulval condyloma as well as within the carcinoma. This case is unusual in that SCC associated with HPV 6/11 developed in her vulva affected by MRS rather than in the cervix, where SCC was more likely to occur considering this patient's age. |
| Databáze: | OpenAIRE |
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