Effects of the interaction between ferric iron and L-dopa melanin on T1 and T2 relaxation times determined by magnetic resonance imaging
Autor: | Anton N. Hasso, David B. Hinshaw, Louis P. Bozzetti, Barbara A. Holshouser, Roland C. Aloia, James P. MacMurray, Jeffrey M. Tosk, A. Douglas Will |
---|---|
Rok vydání: | 1992 |
Předmět: |
Melanins
inorganic chemicals medicine.diagnostic_test Chemistry Relaxation (NMR) Spin–lattice relaxation Magnetic resonance imaging Ferric Compounds Magnetic Resonance Imaging Basal Ganglia Levodopa Models Structural Melanin Spin–spin relaxation Paramagnetism Nuclear magnetic resonance Neuromelanin T2 relaxation medicine Humans Radiology Nuclear Medicine and imaging |
Zdroj: | Magnetic Resonance in Medicine. 26:40-45 |
ISSN: | 1522-2594 0740-3194 |
DOI: | 10.1002/mrm.1910260105 |
Popis: | T1 and T2 relaxation times of agar phantoms containing L-dopa melanin and Fe3+ were measured under MRI conditions. Fe3+ shortened T1 and T2 relaxation times. Melanin influenced relaxation times only in the presence of Fe3+; thus, contrast in MR images of the basal ganglia may depend upon levels of both paramagnetic iron and neuromelanin. |
Databáze: | OpenAIRE |
Externí odkaz: |