Early diagnosis of right ventricular systolic dysfunction by tissue Doppler-derived isovolumic myocardial acceleration in patients with chronic obstructive pulmonary disease
| Autor: | Yelda Tayyareci, Pelin Bayazit, Cagla Pinar Tastan, Gulsah Tayyareci, F.E.S.C. Yilmaz Nisanci M.D. |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Ventricular Dysfunction Right Acceleration Pulmonary disease Doppler imaging Sensitivity and Specificity FEV1/FVC ratio Pulmonary Disease Chronic Obstructive medicine.artery Internal medicine Image Interpretation Computer-Assisted Medicine Humans Radiology Nuclear Medicine and imaging Respiratory function Isovolumetric contraction Subclinical infection COPD business.industry Reproducibility of Results Middle Aged medicine.disease respiratory tract diseases Early Diagnosis Pulmonary artery Cardiology Elasticity Imaging Techniques Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Echocardiography (Mount Kisco, N.Y.). 26(9) |
| ISSN: | 1540-8175 |
| Popis: | OBJECTIVES The aim of the study was to assess validity of tissue Doppler imaging (TDI)-derived right ventricular (RV) myocardial systolic velocities in early detection of RV systolic dysfunction in chronic obstructive pulmonary disease (COPD). METHODS Ninety COPD patients (50 pure COPD and 40 with right heart failure [RHF]) and 40 controls were enrolled. Respiratory function tests, conventional echocardiographic parameters, and TDI-derived isovolumic myocardial acceleration (IVA), peak myocardial velocity during isovolumic contraction (IVV), peak velocity during systolic ejection (Sa) were measured. RESULTS All the TDI-derived RV systolic velocities were impaired in COPD (P = 0.0001) compared to controls. IVA was the only parameter that could distinguish the patients with pure COPD and COPD with RHF (P = 0.0001). IVA was found to be significantly correlated with FEV1 (r = 0.41, P = 0.0001), FEV1/FVC (r = 0.43, P = 0.0001), pulmonary artery pressure (r =-0.34, P = 0.001), pulmonary flow acceleration time (r = 0.48, P = 0.0001), and tricuspid annular systolic excursion (r =-0.41, P = 0.0001). In addition, IVA < or = 2.7 m/sec(2) was able to predict COPD patients from controls with 81% sensitivity, 98% specificity and IVA < or = 1.9 m/sec(2) predicted COPD patients accompanied by RHF with 82% sensitivity, 77% specificity from patients without RHF. CONCLUSIONS TDI-derived RV IVA is a novel, noninvasive echocardiographic index which may be used in the assessment of subclinical RV dysfunction in patients with COPD. |
| Databáze: | OpenAIRE |
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