Aspirin for prophylaxis against headache at high altitudes: randomised, double blind, placebo controlled trial
| Autor: | Michael Philadelphy, Rudolf Likar, Werner Nachbauer, Martin Burtscher |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Placebo-controlled study Altitude Sickness Placebo law.invention Randomized controlled trial Double-Blind Method law Heart Rate medicine Humans Altitude sickness General Environmental Science Aspirin business.industry Anti-Inflammatory Agents Non-Steroidal General Engineering Headache General Medicine Effects of high altitude on humans medicine.disease Oxygen Anesthesia Chemoprophylaxis Papers General Earth and Planetary Sciences Female Headaches medicine.symptom business human activities medicine.drug |
| Zdroj: | BMJ (Clinical research ed.). 316(7137) |
| ISSN: | 0959-8138 3000-5000 |
| Popis: | At altitudes of 3000-5000 m about 20-50% of skiers and mountaineers experience headache, the main symptom of acute mountain sickness.1 Although most mountaineers know that they should avoid climbing great heights too early on and too fast, they may not always act accordingly. The use of drugs to prevent and treat headaches at high altitudes is therefore widespread, aspirin being one of the most commonly taken. We tested the efficacy of aspirin as prophylaxis against headache at high altitudes. Twenty nine volunteers with a history of headache at high altitude were randomly assigned in a double blind fashion to receive placebo (eight men, six women, mean age 38 (SD 12) years) or 320 mg aspirin (nine men, six women, mean age 38 (14) years). After examination at low altitude (600 m), subjects were transported to high altitude (3480 m) … |
| Databáze: | OpenAIRE |
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