Utility of point shear wave elastography in characterisation of focal liver lesions
| Autor: | Heba Omar, Maha S. Hasab Allah, Mohamad Saeed Marie, Ahmed Alsaeed Mandur, Rabab Salama |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Carcinoma Hepatocellular 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Humans Medicine Point (geometry) Aged Aged 80 and over Shear wave elastography Hepatology business.industry Liver Neoplasms Gastroenterology Reproducibility of Results Middle Aged Prognosis Liver ROC Curve Focal Nodular Hyperplasia Area Under Curve Elasticity Imaging Techniques Female 030211 gastroenterology & hepatology Hemangioma business Biomedical engineering |
| Zdroj: | Expert Review of Gastroenterology & Hepatology. 12:201-207 |
| ISSN: | 1747-4132 1747-4124 |
| DOI: | 10.1080/17474124.2018.1415144 |
| Popis: | The present study aimed at evaluation of the usefulness of point shear wave elastography (pSWE) in characterization of FLL(s) by quantifying their stiffness.In total, 197 patients (mean age was 56.57 years) with FLL(s) on conventional ultrasound were included. Final diagnoses, confirmed by imaging and/or biopsy whenever possible, included hepatocellular carcinoma (HCC) (n = 143), metastasis (n = 36), hemangioma (n = 16), and focal nodular hyperplasia (n = 2). Stiffness evaluation was performed by pSWE. Stiffness ratio (lesion to background liver) was calculated. ROC analysis was performed to evaluate the diagnostic accuracy of the stiffness value and stiffness ratio and to extract the optimal cutoff values for characterisation of FLL(s).HCC was significantly softer than its surrounding liver parenchyma [5.43 (3.03) vs. 17.05 (8.53) kPa, p0.001]. However, the stiffness values for the other examined FLLs were comparable to their surrounding liver parenchyma. No significant difference was detected across different types of metastases or between metastases and surrounding liver (p0.05). Stiffness ratio was superior to stiffness value in discrimination of HCC from metastasis (AUROC, 0.91 vs. 0.51 respectively).pSWE could provide a complementary information about FLLs especially in differentiation between HCCs from metastases. |
| Databáze: | OpenAIRE |
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