Decision-Making Strategy for Rectal Cancer Management Using Radiation Therapy for Elderly or Comorbid Patients
| Autor: | Elizabeth Poplin, Salma K. Jabbour, Sarah S. Kılıç, Lara Hathout, Nell Maloney-Patel, Shang-Jui Wang, Usha Malhotra |
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| Rok vydání: | 2018 |
| Předmět: |
Cancer Research
medicine.medical_specialty Colorectal cancer medicine.medical_treatment Brachytherapy Clinical Decision-Making Decision Making MEDLINE Comorbidity 030230 surgery 03 medical and health sciences 0302 clinical medicine Humans Medicine Radiology Nuclear Medicine and imaging Patient participation Intensive care medicine Aged Radiation Rectal Neoplasms business.industry Incidence (epidemiology) Standard treatment Age Factors medicine.disease Clinical trial Radiation therapy Oncology Chemotherapy Adjuvant 030220 oncology & carcinogenesis Patient Participation business Algorithms |
| Zdroj: | International Journal of Radiation Oncology*Biology*Physics. 100:926-944 |
| ISSN: | 0360-3016 |
| Popis: | Rectal cancer predominantly affects patients older than 70 years, with peak incidence at age 80 to 85 years. However, the standard treatment paradigm for rectal cancer oftentimes cannot be feasibly applied to these patients owing to frailty or comorbid conditions. There are currently little information and no treatment guidelines to help direct therapy for patients who are elderly and/or have significant comorbidities, because most are not included or specifically studied in clinical trials. More recently various alternative treatment options have been brought to light that may potentially be utilized in this group of patients. This critical review examines the available literature on alternative therapies for rectal cancer and proposes a treatment algorithm to help guide clinicians in treatment decision making for elderly and comorbid patients. |
| Databáze: | OpenAIRE |
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