Sparsomycin analogs. IV. Synthesis and antitumor activity of pyrimidine-5-carboxamides and (E)-beta-(pyrimidin-5-yl)acrylamides
| Autor: | Tetsuko Hase, Sotoo Nagai, Shizuo Fukuda, Motohiro Tanaka, Masakatsu Yomei, Akimori Wada, Takuma Sasaki, Shoichi Kanatomo |
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| Rok vydání: | 1988 |
| Předmět: |
Antitumor activity
Acrylamides Antibiotics Antineoplastic Pyrimidine Chemical Phenomena Stereochemistry Biological activity Antineoplastic Agents Sparsomycin General Chemistry General Medicine Condensation reaction chemistry.chemical_compound Chemistry Mice Pyrimidines chemistry Drug Discovery Chemical reduction Animals Cells Cultured |
| Zdroj: | Chemicalpharmaceutical bulletin. 36(6) |
| ISSN: | 0009-2363 |
| Popis: | Synthese et etude biologique des composes du titre N-substitues par carboxy-1'-, methoxycarbonyl-1'- ou hydroxymethyl-1' alkyl, la partie pyrimidine etant elle-meme substituee par dimethoxy-2,4 methyl-6 ou dioxo-1,3 tetrahydro-1,2,3,4 trimethyl-1,3,6 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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