Serohematologic Alterations in Broiler Chicks on Feed Amended with Fusarium Proliferatum Culture Material or Fumonisin B1 and Moniliformin
| Autor: | Glenn A. Bennett, L. Marie Côté, J. L. Richard, Mary Ann Dombrink-Kurtzman, William B. Buck, Tariq Javed |
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| Rok vydání: | 1995 |
| Předmět: |
Blood Glucose
Male 0301 basic medicine Time Factors Globulin 040301 veterinary sciences 030106 microbiology Fusarium proliferatum Fumonisins Blood Urea Nitrogen Microbiology 0403 veterinary science Hemoglobins Leukocyte Count 03 medical and health sciences chemistry.chemical_compound Animal science Fusarium Animals Fumonisin B2 Fumonisin B1 General Veterinary biology Sodium Broiler Albumin 04 agricultural and veterinary sciences Hemagglutination Inhibition Tests Mycotoxins biology.organism_classification Animal Feed Enzymes Cholesterol Teratogens chemistry Creatinine Food Fortified Erythrocyte Count biology.protein Alkaline phosphatase Chickens Moniliformin Cyclobutanes |
| Zdroj: | Journal of Veterinary Diagnostic Investigation. 7:520-526 |
| ISSN: | 1943-4936 1040-6387 |
| Popis: | Two hundred twenty-eight male broiler chicks (Columbia x New Hampshire) were given feed amended with autoclaved culture material of Fusarium proliferatum containing fumonisin B1 (FB1) at 61, 193, and 546 ppm, fumonisin B2 (FB2) at 14, 38, and 98 ppm, and moniliformin at 66, 193, and 367 ppm in 3 separate feeding trials (amounts of toxin in each trial, respectively). Birds were started on amended rations at days 1, 7, and 21 and continued on their respective ration until they were 28 days old. Purified FB1 (125, 274 ppm) and moniliformin (27, 154 ppm) were given separately and in combination (137 and 77 ppm, respectively), starting on day 1 and continuing for 14 days. Of serum chemistry parameters, only glucose was significantly decreased. Significant increases were noted in serum cholesterol, sodium, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, and γ-glutamyl transferase. Of the hematologic parameters, significant decreases were noted in red blood cell counts, hemoglobin, packed cell volume, and white blood cell counts. Immunologic changes included impaired anti-Newcastle disease antibody hemagglutination inhibition titers associated with relative decreases in total serum globulins and increases in albumin/globulin ratios. The changes were noted in all treatment groups when compared to controls. |
| Databáze: | OpenAIRE |
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