Atividade secretória uterina e histologia de cadelas pré-púberes em um modelo animal de ablação parcial do desenvolvimento das glândulas uterinas
| Autor: | Bianca B. Martins, Patrícia Maria Coletto Freitas, N. S. Teixeira, Marcelo R. Luz, Juliana Di Giorgio Giannotti, Mariana Machado-Neves, Stéphanie Asséf Millen Valente Teixeira, Louisiane de Carvalho Nunes |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
dogs
desenvolvimento Veterinary medicine Uterus ablação glandular morfologia Female reproductive system Endometrium bitch secreção Masson's trichrome stain Andrology histology 03 medical and health sciences endometrial glands cadela 0302 clinical medicine Trichrome histologia SF600-1100 morphology Medicine prepubertal development medroxiprogesterone acetate modelo animal 030219 obstetrics & reproductive medicine acetato de medroxiprogesterona General Veterinary business.industry pré-púberes 0402 animal and dairy science Myometrium cadelas Uterine horns Histology glandular ablation glândula uterina 04 agricultural and veterinary sciences 040201 dairy & animal science secretion medicine.anatomical_structure ablação parcial partial ablation Útero business |
| Zdroj: | Pesquisa Veterinária Brasileira, Volume: 40, Issue: 2, Pages: 134-140, Published: 13 APR 2020 Pesquisa Veterinária Brasileira, Vol 40, Iss 2, Pp 134-140 (2020) Pesquisa Veterinária Brasileira v.40 n.2 2020 Pesquisa Veterinária Brasileira Colégio Brasileiro de Patologia Animal (CBPA) instacron:EMBRAPA |
| Popis: | Inadequate exposure of the female reproductive system to steroids in uterine developmental periods can partially inhibit the development of endometrial glands in dogs. However, the effects of steroids on the formed glands functionality remain unknown, as well as the possible occurrence of endometrial fibrosis. This study aimed to evaluate the secretory activity of endometrial glands in prebubertal female dogs submitted to a protocol of partial ablation of the uterine adenogenesis. Sixteen females of non-specific breed were distributed into two groups; MPA (n=8), females that received applications of medroxyprogesterone acetate every 3 weeks; and C (n=8) untreated control females. Ovariohysterectomy was performed in all animals at the age of 6 months and evaluated the uterine horns by histological and histochemistry exams. The secretion intensity (degrees 1-4) was evaluated using periodic acid-Schiff (PAS) and alcian blue (AB) pH 2.5. Histological evaluation was performed using Masson’s trichrome and toluidine blue. Only degree 1 and 2 marks for PAS were observed in both groups, with no difference of uterine secretion intensity between the groups regarding the degrees found. However, the MPA group revealed higher intensity of uterine secretion compared to group C (p |
| Databáze: | OpenAIRE |
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