Vaginal carriage and neonatal acquisition of Clostridium difficile
| Autor: | Sheila M. O'farrell, Soad Tabaqchali, J Q Nash, Mark Wilks |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Biology Microbiology Feces Pregnancy medicine Humans Sex organ Clostridium Obstetrics Infant Newborn General Medicine Clostridium difficile Delivery Obstetric medicine.disease Culture Media medicine.anatomical_structure Carriage Vagina Clostridium Infections Gestation Female |
| Zdroj: | Journal of Medical Microbiology. 18:47-53 |
| ISSN: | 1473-5644 0022-2615 |
| DOI: | 10.1099/00222615-18-1-47 |
| Popis: | SUMMARY. The relationship between vaginal carriage and subsequent neonatal acquisition of Clostridium difficile was investigated. Vaginal carriage of C. difficile was detected in 11% of women attending the Department of Genital Medicine Clinic. C. difficile was isolated from the vagina in 18% of 50 mothers before delivery, and 8% after delivery; 62% of their babies had positive faecal cultures. Eight of nine of the babies whose mothers had positive cultures before delivery became colonised with C. difficile, while 23 of 41 babies whose mothers had negative cultures became colonised. This suggests that both the vagina and the environment may act as sources of neonatal acquisition of C. difficile. Broth enrichment culture proved a more sensitive method for isolating C. difficile from the vagina than direct plate culture and should be used in such investigations. |
| Databáze: | OpenAIRE |
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