Ion Selective PVC Membrane Electrode for the Determination of Methacycline Hydrochloride in Pharmaceutical Formulation
Autor: | Hassan Y. Aboul-Enein, Xian Xiang Sun, Cheng Jun Sun |
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Rok vydání: | 2002 |
Předmět: |
Detection limit
Methacycline Ion-selective electrode Potentiometry Drug analysis Chromatography Chemistry Pharmaceutical formulation lcsh:Chemical technology Biochemistry Methacycline hydrochloride Atomic and Molecular Physics and Optics Analytical Chemistry Ion Ion selective electrode Membrane Electrode lcsh:TP1-1185 Electrical and Electronic Engineering Instrumentation Nuclear chemistry |
Zdroj: | Sensors, Vol 2, Iss 10, Pp 424-431 (2002) Sensors; Volume 2; Issue 10; Pages: 424-431 |
ISSN: | 1424-8220 |
DOI: | 10.3390/s21000424 |
Popis: | A plastic membrane electrode for the determination of methacycline hydrochloride was fabricated based on the use of methacycline-tetraphenylborate as the electroactive substance, and dioctylphtalate as the plasticizing agent. It was found that the potential responses of the electrode were influenced by pH of the tested solution when pH>3. Under the condition of pH 2.6, the linear response range, slope (25ºC) and detection limit obtained were 3.0×10-2~6.0×10-6M, 52.9mv per decade and 3.4×10-6M ,respectively. The response time of the electrodes was |
Databáze: | OpenAIRE |
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