| Přispěvatelé: |
Brandimarte, Giovanni, Frajese, Giovanni V, Bargiggia, Stefano, Castellani, Danilo, Cocco, Andrea, Colucci, Raffaele, Evangelista, Enrica, Gravina, Antonietta G, Napoletano, Domenico, Nardi, Elisabetta, Maisto, Tammaro, Morabito, Antonino, Pianese, Giuseppe, Romano, Antonio, Sacco, Rodolfo, Sediar I, Luca, Sinnona, Nicola, Tifi, Lorenza, Davino, Alessandro, Elisei, Walter, Tursi, Antonio |
| Popis: |
Background: Symptomatic uncomplicated diverticular disease (SUDD) is a recognized clinical condition characterized by abdominal pain and changes in bowel habits, attributed to diverticula but without macroscopic signs of diverticulitis. There is no consensus about the management of these patients. Enteroflegin®, an association of natural active ingredients, could be effective in the treatment of those patients. Methods: We conducted a retrospective observational study to evaluate the performances of Enteroflegin® in patients with SUDD. Patients were treated with Enteroflegin® 2 cp/day for 10 days per month for 6 months. Primary endpoint was the clinical remission rate, defined as the absence of any symptoms; secondary endpoints were the impact of the treatment on reduction of symptoms, on fecal calprotectin (FC) expression, and the prevention of acute diverticulitis. Results: Three hundred and fifty patients were retrospectively enrolled (183 males, median age 64 yrs, IQR 54-70). Enteroflegin® was effective in inducing remission in 9.34% and 17.64% of patients at 3 and 6 months respectively (p |
