Recurrent hungry bone syndrome in a kidney transplant recipient with a history of parathyroidectomy: A case report
| Autor: | Lo-Yi Ho, Kai-Chun Chan, Ping-Nam Wong, Wing-Tung Kwok, Siu-Ka Mak, Man-Wai Lo, Shuk-Fan Chan, Kin-Yee Lo, Ho-Kwan Sin, Kwok-Chi Lo, Yuk-Yi Wong |
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| Rok vydání: | 2021 |
| Předmět: |
Parathyroidectomy
medicine.medical_specialty RD1-811 medicine.medical_treatment Urology Parathyroid hormone Renal function 030230 surgery Hypomagnesemia Bone remodeling Kidney transplantation 03 medical and health sciences 0302 clinical medicine Calcium-sensing receptor medicine Transplantation business.industry Acute kidney injury Hungry bone syndrome medicine.disease 030211 gastroenterology & hepatology Surgery business Renal osteodystrophy Adynamic bone disease Hypophosphatemia |
| Zdroj: | Transplantation Reports, Vol 6, Iss 3, Pp 100074-(2021) |
| ISSN: | 2451-9596 |
| Popis: | Background: The hungry bone syndrome (HBS) is a well described phenomenon occurring shortly after parathyroidectomy characterized by rapid bone formation with concomitant hypocalcemia, hypophosphatemia and hypomagnesemia requiring intensive management. Recurrent HBS occurring in isolation from parathyroidectomy has not been reported.Case presentation: We describe a case of recurrent HBS in a kidney transplant recipient (KTR) developing years after parathyroidectomy. The KTR was a 49 year-old lady who had undergone successful total parathyroidectomy without re-implantation 14 years prior and cadaveric kidney transplantation 12 years prior. She had a stable creatinine level of 220μmol/L and an estimated glomerular filtration rate (eGFR) of 20 mL/min-1.73m2. She presented to us with severe hypercalcemia, likely a result of excessive calcium and vitamin D supplementation, and acute kidney injury. Serum creatinine, calcium, phosphate, magnesium, alkaline phosphatase (ALP), and intact parathyroid hormone (iPTH) levels on admission were 743μmol/L, 4.8 mmol/L, 1.8 mmol/L, 0.75 mmol/L, 48IU/L and |
| Databáze: | OpenAIRE |
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