Features and roles of T helper 22 cells in immunological diseases and malignancies
| Autor: | Nikoo Hossein-Khannazer, Zeineb Zian, Reza Yazdani, Joaira Bakkach, Abubakar Umar Anka, Ramin Hosseinzadeh, Ali N. Kamali, Gholamreza Azizi |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Immunology Cell Disease Autoimmune Diseases Pathogenesis 03 medical and health sciences 0302 clinical medicine Neoplasms Hypersensitivity medicine Humans Inflammation Autoimmune disease Epithelial barrier business.industry Interleukins Interleukin Cancer T-Lymphocytes Helper-Inducer General Medicine medicine.disease Lymphocyte Subsets 030104 developmental biology medicine.anatomical_structure Immunological diseases business 030215 immunology |
| Zdroj: | Scandinavian Journal of Immunology. 93 |
| ISSN: | 1365-3083 0300-9475 |
| Popis: | T helper 22 (Th22) cell populations are a newly identified subset of CD4+ T cells that primarily mediate biological effects on the epithelial barrier through interleukin (IL)-22. Although, new studies showed that both Th22 and IL-22 are closely associated with the pathogenesis of inflammatory, autoimmune and allergic disease as well as malignancies. In this review, we aim to describe the development and characteristics of Th22 cells as well as their roles in the immunopathogenesis of immune-related disorders and cancer. © 2021 The Scandinavian Foundation for Immunology |
| Databáze: | OpenAIRE |
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