Absorption of Amorolfine through Human Nail
| Autor: | Franz Tj |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Antifungal Agents
Morpholines Skin Absorption Dermatology Absorption (skin) In Vitro Techniques Pharmacology Chloride Absorption Lacquer chemistry.chemical_compound Amorolfine medicine Humans Methylene Methylene Chloride Ethanol integumentary system Permeation medicine.anatomical_structure Nails chemistry visual_art visual_art.visual_art_medium Nail (anatomy) Nuclear chemistry medicine.drug |
| Zdroj: | Dermatology. 184:18-20 |
| ISSN: | 1421-9832 1018-8665 |
| DOI: | 10.1159/000247611 |
| Popis: | The percutaneous absorption of a new antifungal agent, amorolfine, has been measured through both skin and nail using an in vitro technique. Application of a 5% concentration in either an ethanol or methylene chloride lacquer resulted in permeation rates through nail in the range of 20-100 ng/cm2/h and somewhat higher through skin. Absorption was greater from the methylene chloride lacquer than the ethanol lacquer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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