Increased coagulation factor levels leading to allograft renal vein thrombosis
| Autor: | Moshe Zlotnik, Michael J. Hausmann, Aaron Tomer, Boris Rogachev, Marina Vorobiov |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Graft Rejection
Male medicine.medical_specialty Thrombophilia Gastroenterology Renal Veins Factor IX Internal medicine medicine Humans Homocysteine Factor XI Clotting factor Venous Thrombosis Factor VIII business.industry Graft Survival Renal vein thrombosis General Medicine Factor VII Middle Aged medicine.disease Thrombosis Kidney Transplantation Blood Coagulation Factors Surgery Venous thrombosis surgical procedures operative Nephrology Allograft Thrombosis Renal vein business Kidney disease |
| Zdroj: | Clinical nephrology. 61(3) |
| ISSN: | 0301-0430 |
| Popis: | A patient with end-stage kidney disease is described, who lost his renal allograft in the early post-transplant period due to allograft renal vein thrombosis. Prior to transplantation, he had been treated by hemodialysis and lost several vascular accesses because of thrombosis. A search for potential thrombophilic factors disclosed a unique combination of increased clotting factor levels, i.e. FVIII, FIX, FXI and homocysteine. More common hereditary and acquired hypercoagulability factors have been excluded in this patient. While clotting factor deficiencies are well known causes of hemophilia, their levels should also be measured in the workup of transplant candidates with a history of multiple vascular access thrombosis. |
| Databáze: | OpenAIRE |
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