The efficacy of intravenous paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children
| Autor: | Hale Yarkan Uysal, Hülya Başar, Suna Akin Takmaz, Bülent Baltaci, Ferda Yaman |
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| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Sedation medicine.medical_treatment Analgesic law.invention Pacu Adenoidectomy Postoperative Complications Patient satisfaction Double-Blind Method Randomized controlled trial law medicine Humans Child Infusions Intravenous Psychomotor Agitation Tramadol Acetaminophen Pain Measurement Tonsillectomy Pain Postoperative biology business.industry Analgesics Non-Narcotic biology.organism_classification Surgery Analgesics Opioid Anesthesiology and Pain Medicine Patient Satisfaction Anesthesia Postoperative Nausea and Vomiting Female medicine.symptom Anesthesia Inhalation business Postoperative nausea and vomiting medicine.drug |
| Zdroj: | Journal of Clinical Anesthesia. 23:53-57 |
| ISSN: | 0952-8180 |
| DOI: | 10.1016/j.jclinane.2010.07.001 |
| Popis: | Study Objective To evaluate the efficacy and the quality of recovery with intravenous (IV) paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children. Design Prospective, randomized, double-blinded clinical trial. Setting Operating room and Postanesthesia Care Unit (PACU) of a university-affiliated hospital. Patients 64 ASA physical status I and II children, aged 6 to 16 years, scheduled for adenotonsillectomy. Interventions All patients were premedicated with oral midazolam 0.5 mg/kg 30 minutes before surgery. Patients were randomized to two groups following induction of general anesthesia. The paracetamol group (n = 32) received 15 mg/kg of IV paracetamol and the tramadol group (n = 32) received 1.0 mg/kg of IV tramadol. Measurements Modified Hannallah pain scores, emergence agitation, Aldrete scores, sedation scores, time to first administration of analgesic, heart rate, and mean arterial blood pressure were recorded for each patient. Data were recorded every 5 minutes for the first 30 minutes and every 10 minutes for the remaining 30 minutes in the PACU, then at 2, 3, 4, 5, 6, 8, 12, and 24 hours in the ward. The frequency of postoperative nausea and vomiting also was noted. Satisfaction of parents and nurses was determined on a 4-point scale at the end of the study. Main Results No significant demographic differences between groups were noted. No statistically significant difference was found in postoperative pain scores in either group. Agitation scores, Aldrete scores, sedation scores, and number of patients who received rescue analgesia and time to administration of rescue analgesia were similar in both groups. Conclusions The IV formulation of paracetamol was associated with similar analgesic properties and early recovery to that of IV tramadol after adenotonsillectomy in children. |
| Databáze: | OpenAIRE |
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