Comparison of the effect of rapeseed oil or amaranth seed oil supplementation on weight loss, body composition, and changes in the metabolic profile of obese patients following 3-week body mass reduction program: a randomized clinical trial

Autor: Aldona Juchacz, Marian Grzymisławski, Paweł Bogdański, Agnieszka Zawada, Małgorzata Moszak
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Blood Glucose
Male
0301 basic medicine
Weight loss
Endocrinology
Diabetes and Metabolism
Clinical Biochemistry
Body water
Body composition
Body Mass Index
chemistry.chemical_compound
0302 clinical medicine
Endocrinology
Medicine
Rapeseed oil
lcsh:RC620-627
Amaranthus
Anthropometry
Middle Aged
lcsh:Nutritional diseases. Deficiency diseases
Metabolome
Homeostatic model assessment
Female
Waist Circumference
medicine.symptom
medicine.medical_specialty
Clinical chemistry
Amaranth seed oil
030209 endocrinology & metabolism
Metabolic profile
Intra-Abdominal Fat
03 medical and health sciences
Insulin resistance
Internal medicine
Humans
Plant Oils
Obesity
Triglycerides
Caloric Restriction
030109 nutrition & dietetics
business.industry
Cholesterol
Research
Body Weight
Biochemistry (medical)
medicine.disease
chemistry
Dietary Supplements
Lean body mass
Insulin Resistance
business
Body mass index
Zdroj: Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-11 (2020)
Lipids in Health and Disease
Popis: Background Amaranth seed oil (ASO) and rapeseed oil (RSO) are functional foods that display antioxidant and hepatoprotective properties. These oils are also known to lower glucose and cholesterol levels. The current study compared the effects exerted by RSO and ASO on weight loss and metabolic parameters during a 3-week body mass reduction program. Methods Eighty-one obese subjects (BMI > 30 kg/m2), aged 25–70 years, were enrolled in a 3-week body mass reduction program based on a calorie-restricted diet and physical activity. Participants were randomly categorized into an AO group (administered 20 mL/d of ASO), a RO group (administered 20 mL/d of RSO), and a C group (control; untreated). Anthropometric and metabolic parameters were measured at baseline and endpoint. Results Significant decreases in weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), fat mass (FM), lean body mass (LBM), visceral fat mass (VFM), and total body water (TBW%) were observed in all groups (P P = 0.034), total cholesterol (Δ -14.6; P = 0.032), non-HDL cholesterol (Δ 15.9; P = 0.010), TG/HDL ratio (Δ -0.6; P = 0.032), LDL cholesterol (Δ -12.3; P = 0.042), and triglycerides (Δ -6.5; P = 0.000) were significantly improved in the AO group, compared to the RO group. Conclusions The 3-week body mass reduction intervention caused a significant reduction in the weight, BMI, WC, HC, FM, and VFM of all groups. Except for HOMA-IR, there were no statistical differences between the clinical parameters of all groups. However, a trend toward improved insulin levels and HDL% was noticeable in AO and RO. Therapies involving edible oils with high nutritional value, such as RSO and ASO, show potential for improving metabolic measurements during body mass reduction programs. Thus, obese patients undertaking weight reduction programs may benefit from RSO and ASO supplementation. Trial registration retrospectively registered, DRKS00017708.
Databáze: OpenAIRE
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