Acupuncture Treatment Associated with Functional Connectivity Changes in Primary Dysmenorrhea: A Resting State fMRI Study

Autor:	Yi-Hung Chen, Cheng-Hao Tu, Yu-Chen Lee, Chun-Ming Chen, Ying-Yu Chen, Wen-Chi Lu, Su Tso Yang
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Resting state fMRI medicine.diagnostic_test business.industry Functional connectivity resting-state functional magnetic resonance imaging functional connectivity General Medicine Acupuncture treatment Article Adult women periaqueductal gray matter Periaqueductal gray matter sanyinjiao Anesthesia medicine Acupuncture descending pain modulation systems Medicine Effective treatment Functional magnetic resonance imaging business primary dysmenorrhea acupuncture
Zdroj:	Journal of Clinical Medicine Volume 10 Issue 20 Journal of Clinical Medicine, Vol 10, Iss 4731, p 4731 (2021)
ISSN:	2077-0383
Popis:	Primary dysmenorrhea (PDM) is the most commonly encountered gynecological problem in reproductive-age women. Acupuncture has been suggested as an effective treatment of PDM that may modulate descending pain modulation systems. In the present study, we used resting-state functional magnetic resonance imaging to investigate possible changes in descending pain modulation systems after acupuncture treatment in women with PDM. Thirty-four right-handed adult women with PDM participated in this randomized, single-blinded, sham-controlled study. Each patient was randomly allocated to an 8-week verum or sham acupuncture intervention on the bilateral Sanyinjiao (SP6). Resting-state functional magnetic resonance imaging was conducted before, during, and after the intervention to measure the spontaneous activity in brain. After the 8-week intervention, both verum and sham groups reported decreased menstrual pain. However, the cessation of decreased functional connectivity (FC) between periaqueductal gray matter and the regions associated with affective pain modulation and attention-related pain modulation were found in the verum but not in the sham group after the 8-week intervention. More decreased FC has been found in the region associated with non-specific effects of acupuncture intervention after the early stage of acupuncture intervention. These results indicated that verum acupuncture may intercept the altered FC in descending pain modulation systems in PDM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8836100a2c1288c72f16311436d6407e http://europepmc.org/articles/PMC8537009 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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