The Extracellular Electron Transport Pathway Reduces Copper for Sensing by the CopRS Two-Component System under Anaerobic Conditions in Listeria monocytogenes
| Autor: | Amena A. Rizk, Gloria Komazin, Michael Maybin, Nushrat Hoque, Emily Weinert, Timothy C. Meredith |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of bacteriology. |
| ISSN: | 1098-5530 |
| Popis: | Two-component extracellular copper sensing from the periplasm of Gram-negative bacteria has been well studied, but copper detection at the cell surface of the Gram-positive L. monocytogenes is less understood. Collectively, our results show that EET is most active under anaerobic conditions and reduces Cu 2+ and Ag 1+ to, respectively, generate or remove the monovalent ligands that directly bind to CopS and lead to the induction of lipoprotein remodeling genes. |
| Databáze: | OpenAIRE |
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