Induction of estrus by prostaglandin F2alpha administration in the vaginal vestibules of miniature pigs
| Autor: | Ikuo Domeki, Yasuo Shioya, Hisataka Iwata, Takeshi Kuge, Yasunori Monji, Takehito Kuwayama |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
endocrine system
medicine.medical_specialty Miniature pig Swine medicine.medical_treatment Luteolysis Prostaglandin Luteal phase Dinoprost chemistry.chemical_compound Estrus Internal medicine Submucosa medicine Animals Saline reproductive and urinary physiology Progesterone Estrous cycle biology Estradiol urogenital system business.industry Embryo biology.organism_classification Administration Intravaginal medicine.anatomical_structure Endocrinology chemistry Animal Science and Zoology Female business hormones hormone substitutes and hormone antagonists |
| Zdroj: | The Journal of reproduction and development. 52(3) |
| ISSN: | 0916-8818 |
| Popis: | Estrus induction is an important step in embryo production. It has been difficult to induce estrus in miniature pigs by intramascular (i.m.) injection of prostaglandin F2alpha (PGF2(2alpha)) in the early luteal stage of the estrous cycle. In the present study, we injected two different doses of PGF2(2alpha) i.m. and into the submucosa of the vaginal vestibule (i.ves.) of miniature pigs, and examined the effect of these treatments on estrus induction. Fifteen miniature pigs were divided into five experimental groups (control, saline injected i.m.; PGF2alpha treated, 1.0 or 1.5 mg of PGF2alpha injected twice i.m. or i.ves.), and the estrus length and concentrations of 17beta-estradiol (E2) and progesterone (P) in the blood were examined. Estrus length was significantly shortened by a large amount of PGF2alpha injected i.ves. In addition, the concentration of P in the blood significantly decreased after two injections of PGF2alpha (i.m. or i.ves.). These results suggest that in miniature pigs, administration of at least 3.0 mg of PGF2alpha is required for the induction of luteolysis and injection of PGF2alpha into the vaginal vestibule is a useful method of estrus induction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|