Fine-needle sampling of primary neuroendocrine carcinomas of salivary glands: Cytohistological correlations and clinical analysis
| Autor: | Réal Lagacé, Jerzy Klijanienko, Vincent Servois, Philippe Vielh, Adel K. El-Naggar, Christian Lussier |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Histology Small-cell carcinoma Pathology and Forensic Medicine Keratin medicine Carcinoma Humans Aged Aged 80 and over chemistry.chemical_classification biology Salivary gland Biopsy Needle Chromogranin A General Medicine Middle Aged Salivary Gland Neoplasms medicine.disease Carcinoma Neuroendocrine medicine.anatomical_structure chemistry Cytopathology biology.protein Female Differential diagnosis Immunostaining |
| Zdroj: | Diagnostic Cytopathology. 24:163-166 |
| ISSN: | 1097-0339 8755-1039 |
| DOI: | 10.1002/1097-0339(200103)24:3<163::aid-dc1034>3.0.co;2-i |
| Popis: | Fine-needle samplings of nine examples of primary neuroendocrine carcinoma of salivary glands were evaluated for their cytologic characteristics and were correlated with the corresponding histological sections. Consistent cytological findings were dispersed or loose clusters of poorly differentiated small- to intermediate-sized cells and occasional smudged nuclei. Mild to moderate nuclear pleomorphism, scant or absent cytoplasm, and nuclear molding were also observed. Rosette-like patterns and multinucleated cells were occasionally seen. Immunostaining of one recent case showed positivity for chromogranin and keratin. The differential diagnosis of primary and metastatic tumors with neuroendocrine features of the salivary glands is discussed. |
| Databáze: | OpenAIRE |
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