Practical experience and challenges in the operation of medical cyclotron
| Autor: | R. G. Sonkawade, Madhavi Tripathi, Nishikant Damle, C S Bal, Praveen Kumar, Rajeev Kumar, Anil Kumar Pandey |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Leak Fluorine Radioisotopes Materials science Maintenance Nuclear engineering Cyclotron Planning target volume chemistry.chemical_element India 030218 nuclear medicine & medical imaging law.invention 03 medical and health sciences 0302 clinical medicine law medicine Humans Radiology Nuclear Medicine and imaging Medical physics Argon Nitrogen Radioisotopes Water General Medicine Pet imaging Cyclotrons Ion source Oxygen chemistry 030220 oncology & carcinogenesis Positron-Emission Tomography Fuse (electrical) Nuclear Medicine Radiopharmaceuticals Beam (structure) |
| Zdroj: | Nuclear medicine communications. 38(1) |
| ISSN: | 1473-5628 |
| Popis: | OBJECTIVE The aim of this article was to share 10 years of operational experience of medical cyclotron and to provide working knowledge on the same. This experience has helped us gain working knowledge on cyclotron operation with practical points, which may help in improving F yield, minimizing the breakdown time, and help in the prevention of the occurrence of unusual events. MATERIALS AND METHODS Our facility has a self-shielded radioisotope delivery system eclipse 111 medical cyclotron with an 11 MeV proton beam in use for the past 10 years to produce positron emitters - namely, F, N, and F-2 gas - for PET imaging. During F production, we have followed a set protocol comprising the following: monitoring target pressure, rinsing the target with O water just immediately after bombardment, ion source feedback, radiofrequency (RF) feedback, and recording any unusual events that occurred during the operation. Besides this, enrichment of O water, target volume, target current, energy of the beam, variation in argon pressure on the target, bombardment duration, target status (new or old target or total number of previous bombardments on the same target), status of the delivery lines from target to the radiochemistry module (old or new) were also recorded. RESULTS Rinsing with O water immediately after bombardment increases the life of the target and delivery line. The frequent problems encountered were with the ion source, RF, and target foil rupture. These problems were solved by rebuilding the ion source, changing the fuse of RF, and rebuilding the target. CONCLUSION F yield can be increased by rinsing with O water immediately after bombardment. The effect of target leak - that is, rupture of vacuum window - can be avoided by immediate stoppage of bombardment. |
| Databáze: | OpenAIRE |
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