Development and validation of a dementia screening tool for primary care in Taiwan: Brain Health Test

Autor: Wen Fu Wang, Jian Liang Liu, Tzung-Jeng Hwang, Ping Huang Tsai, Ming-Chyi Pai, Pei Ning Wang, Chiung Chih Chang, Jen Ping Huang, Ker Neng Lin
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Medical Doctors
Health Care Providers
lcsh:Medicine
Neuropsychological Tests
Alzheimer's Disease
Geographical Locations
0302 clinical medicine
Cognition
Learning and Memory
Medicine and Health Sciences
Medical Personnel
lcsh:Science
Cognitive Impairment
Aged
80 and over

Multidisciplinary
Cognitive Neurology
Neurodegenerative Diseases
Mental Status and Dementia Tests
Test (assessment)
Cognitive test
Professions
Neurology
Female
Research Article
medicine.medical_specialty
Asia
Patients
Clinical Dementia Rating
Cognitive Neuroscience
MEDLINE
Taiwan
Memory and Learning Tests
Diagnosis
Differential

03 medical and health sciences
Memory
Physicians
mental disorders
Mental Health and Psychiatry
medicine
Dementia
Humans
Cognitive Dysfunction
Primary Care
Aged
030214 geriatrics
Receiver operating characteristic
Primary Health Care
business.industry
lcsh:R
Biology and Life Sciences
medicine.disease
Health Care
Early Diagnosis
ROC Curve
People and Places
Physical therapy
Cognitive Science
lcsh:Q
Population Groupings
Differential diagnosis
business
030217 neurology & neurosurgery
Neuroscience
Zdroj: PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0196214 (2018)
ISSN: 1932-6203
Popis: Objectives To develop a simple dementia screening tool to assist primary care physicians in identifying patients with cognitive impairment among subjects with memory complaints or at a high risk for dementia. Design The Brain Health Test (BHT) was developed by several experienced neurologists, psychiatrists, and clinical psychologists in the Taiwan Dementia Society. Validation of the BHT was conducted in the memory clinics of various levels of hospitals in Taiwan. Participants All dementia patients at the memory clinics who met the inclusion criteria of age greater or equal to 50 years were enrolled. Besides the BHT, the Mini-Mental State Examination and Clinical Dementia Rating were used to evaluate the cognition state of the patients and the severity of dementia. Results The BHT includes two parts: a risk evaluation and a cognitive test (BHT-cog). Self or informants reports of memory decline or needing help from others to manage money or medications were significantly associated with cognitive impairment. Among the risk factors evaluated in the BHT, a total risk score greater or equal to 8 was defined as a high risk for dementia. The total score for the finalized BHT-cog was 16. When the cutoff value for the BHT-cog was set to 10 for differentiating dementia and a normal mental state, the sensitivity was 91.5%, the specificity was 87.3%, the positive predictive value was 94.8%, and the negative predictive value was 80.1% The area under the receiver operating characteristic curve between dementia and healthy subjects was 0.958 (95% CI = 0.941-0.975). Conclusions The BHT is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening.
Databáze: OpenAIRE
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