Development and validation of a dementia screening tool for primary care in Taiwan: Brain Health Test
Autor: | Wen Fu Wang, Jian Liang Liu, Tzung-Jeng Hwang, Ping Huang Tsai, Ming-Chyi Pai, Pei Ning Wang, Chiung Chih Chang, Jen Ping Huang, Ker Neng Lin |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Male
Medical Doctors Health Care Providers lcsh:Medicine Neuropsychological Tests Alzheimer's Disease Geographical Locations 0302 clinical medicine Cognition Learning and Memory Medicine and Health Sciences Medical Personnel lcsh:Science Cognitive Impairment Aged 80 and over Multidisciplinary Cognitive Neurology Neurodegenerative Diseases Mental Status and Dementia Tests Test (assessment) Cognitive test Professions Neurology Female Research Article medicine.medical_specialty Asia Patients Clinical Dementia Rating Cognitive Neuroscience MEDLINE Taiwan Memory and Learning Tests Diagnosis Differential 03 medical and health sciences Memory Physicians mental disorders Mental Health and Psychiatry medicine Dementia Humans Cognitive Dysfunction Primary Care Aged 030214 geriatrics Receiver operating characteristic Primary Health Care business.industry lcsh:R Biology and Life Sciences medicine.disease Health Care Early Diagnosis ROC Curve People and Places Physical therapy Cognitive Science lcsh:Q Population Groupings Differential diagnosis business 030217 neurology & neurosurgery Neuroscience |
Zdroj: | PLoS ONE PLoS ONE, Vol 13, Iss 4, p e0196214 (2018) |
ISSN: | 1932-6203 |
Popis: | Objectives To develop a simple dementia screening tool to assist primary care physicians in identifying patients with cognitive impairment among subjects with memory complaints or at a high risk for dementia. Design The Brain Health Test (BHT) was developed by several experienced neurologists, psychiatrists, and clinical psychologists in the Taiwan Dementia Society. Validation of the BHT was conducted in the memory clinics of various levels of hospitals in Taiwan. Participants All dementia patients at the memory clinics who met the inclusion criteria of age greater or equal to 50 years were enrolled. Besides the BHT, the Mini-Mental State Examination and Clinical Dementia Rating were used to evaluate the cognition state of the patients and the severity of dementia. Results The BHT includes two parts: a risk evaluation and a cognitive test (BHT-cog). Self or informants reports of memory decline or needing help from others to manage money or medications were significantly associated with cognitive impairment. Among the risk factors evaluated in the BHT, a total risk score greater or equal to 8 was defined as a high risk for dementia. The total score for the finalized BHT-cog was 16. When the cutoff value for the BHT-cog was set to 10 for differentiating dementia and a normal mental state, the sensitivity was 91.5%, the specificity was 87.3%, the positive predictive value was 94.8%, and the negative predictive value was 80.1% The area under the receiver operating characteristic curve between dementia and healthy subjects was 0.958 (95% CI = 0.941-0.975). Conclusions The BHT is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening. |
Databáze: | OpenAIRE |
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