An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives
| Autor: | Aleksandra Redzicka, Anna Wójcicka |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
azaizoindoles
medicine.drug_class Stereochemistry lcsh:Medicine lcsh:RS1-441 Pharmaceutical Science biological activity Review Ring (chemistry) Antimycobacterial 01 natural sciences pyrrole heterocycles lcsh:Pharmacy and materia medica chemistry.chemical_compound Drug Discovery Pyridine Structural isomer medicine Moiety analgesic activity Pyrrole Bicyclic molecule 010405 organic chemistry Chemistry structure-activity relationships lcsh:R pyrrolo[3 4-c]pyridine Biological activity 0104 chemical sciences 010404 medicinal & biomolecular chemistry anticancer activity Molecular Medicine |
| Zdroj: | Pharmaceuticals, Vol 14, Iss 354, p 354 (2021) Pharmaceuticals |
| ISSN: | 1424-8247 |
| Popis: | Pyrrolo[3,4-c]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-c]pyridine derivatives is the main reason for developing new compounds containing this scaffold. This review presents studies on the biological activity of pyrrolo[3,4-c]pyridines that have been reported in the scientific literature. Most of these derivatives have been studied as analgesic and sedative agents. Biological investigations have shown that pyrrolo[3,4-c]pyridines can be used to treat diseases of the nervous and immune systems. Their antidiabetic, antimycobacterial, antiviral, and antitumor activities also have been found. |
| Databáze: | OpenAIRE |
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