Aeroallergen sensitization in Lebanese asthmatic children: the results of a cohort national study

Autor: Pierre Hage, Salman Mroueh, Paul-Henry Torbey, Edgard Asmar, Nelly Yazbek, Souheil Hallit, Marie Samarani, George Abi Fares, Hala Feghali Abiad, Valeria Modica Alameddine, Marie-Claude Fadous Khalife
Rok vydání: 2019
Předmět:
Zdroj: Environmental Science and Pollution Research. 27:5597-5605
ISSN: 1614-7499
0944-1344
Popis: Atopic asthma is characterized by the presence of sensitization to common aeroallergens, which tends to have a worse prognosis than non-atopic asthma. The objectives were to determine the prevalence of aeroallergens sensitization in the Lebanese pediatric asthmatic population and determine the relationship between allergens sensitization (indoor and outdoor) and age, area of residence and altitude. A sample, consisting of 919 asthmatic children (aged 1 to 18 years, from 2010 until 2017), underwent skin prick testing (SPT) with 21 common allergens: 5 grasses (cocksfoot, sweet vernal-grass, rye-grass, meadow grass, timothy), Parietaria, olive, Dermatophagoides pteronyssinus and Dermatophagoides farina (DP-DF), dog and cat dander, Alternaria longipens, Aspergillus fumigatus and nidulans, Cupressaceae, pine, German cockroach, and 4 cereals (oat, wheat, barley, maize). Seven hundred fifty-two patients had positive SPT. The distribution of sensitization was as follows: DP-DF 59%; 5 grasses 34%; 4 cereals 33.9%; cat 29.9%; Alternaria 27.9%; Parietaria 23%; dog 21.9%; olive 20.5%; Aspergillus mix 18.6%; Cupressaceae 18.2%; pine 17%; cockroach 15.3%. House dust mites sensitization was frequent at lower altitude (
Databáze: OpenAIRE