Pollen Typhae total flavone improves insulin resistance in high-fat diet and low-dose streptozotocin-induced type 2 diabetic rats
| Autor: | Zhen Xie, Xiao Liang, Jing Leng, Ze-Hui Jiang, Qun Chen, Wei Zhao, Xiao-Tao Feng |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Glucose uptake Type 2 diabetes Biology Diet High-Fat Typhaceae medicine.disease_cause Applied Microbiology and Biotechnology Biochemistry Diabetes Mellitus Experimental Analytical Chemistry Eating Insulin resistance In vivo Internal medicine Pollen medicine Animals Molecular Biology Dose-Response Relationship Drug Body Weight Organic Chemistry General Medicine Flavones medicine.disease Streptozotocin Lipids In vitro Rats Endocrinology Insulin Resistance Dyslipidemia Biotechnology medicine.drug |
| Zdroj: | Bioscience, Biotechnology, and Biochemistry. 78:1738-1742 |
| ISSN: | 1347-6947 0916-8451 |
| DOI: | 10.1080/09168451.2014.930318 |
| Popis: | Pollen Typhae total flavone (PTF), the extract from Pollen Typhae, is reported to enhance glucose uptake in C2C12 myotubes in vitro, but the convincing evidence is lacking in vivo. In this study, PTF ameliorated insulin resistance and dyslipidemia, but failed to significantly increase body weight in type 2 diabetic rats induced by high-fat diet and low-dose streptozotocin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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