Occupational risks for uveal melanoma results from a case-control study in nine European countries

Autor: Ian A. Cree, Franco Merletti, Janine Bell, Lene Clausen, Mikael Eriksson, Ana Miranda, Aivars Stengrevics, Wolfgang Ahrens, Noemia Afonso, María Morales-Suárez-Varela, Lennart Hardell, Joelle Fevotte, Karl-Heinz Jöckel, Jean-Michel Lutz, Tine K. Kvist, Terri J. Ballard, Elsebeth Lynge, Svend Sabroe, Pascal Guénel, Diane Cyr
Přispěvatelé: Secretariat, U754, Registre Genevois des Tumeurs, CHU Genève, Translational Oncology Research Centre, Queen Alexandra Hospital, Aarhus University [Aarhus], Department of Public Health [Copenhagen], Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Department of Biostatistics and Medical Informatics, Universidade do Porto = University of Porto, Bremen Institute for Prevention Research and Social Medicine, The Venetian Tumour Registry, Hôpital de Padoue, Thames Cancer Registry, Hôpital Londres, Santé publique et épidémiologie des déterminants professionnels et sociaux de la santé, Epidémiologie, sciences sociales, santé publique (IFR 69), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Oncology, Lund University Hospital, Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement UMRT9002 (UMRESTTE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche sur les Transports et leur Sécurité (INRETS)-Institut de Veille Sanitaire (INVS), Recherches épidémiologiques et statistiques sur l'environnement et la santé., Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Örebro University Hospital [Örebro, Sweden], University Clinics of Essen, University of Essen, Southern Portugal Cancer Registry, Instituto Português de Oncologia, Unit of Cancer Epidemiology, Université de Turin-CERMS and Centre for Oncologic Prevention, Unit of Public Health and Environmental Care, Universitat de València (UV), Latvia Cancer Register, Latvia Oncology Centre, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Universidade do Porto, Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris-Sud - Paris 11 (UP11)-École des hautes études en sciences sociales (EHESS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Université de Valence, Institut National de Recherche sur les Transports et leur Sécurité (INRETS)-Institut de Veille Sanitaire (INVS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Male
Uveal Neoplasms
Cancer Research
Medizin
Uveal Neoplasm
MESH: Risk Assessment
MESH: Occupational Exposure
0302 clinical medicine
Reference Values
Epidemiology
Medicine
MESH: Incidence
Melanoma
MESH: Aged
MESH: Middle Aged
Incidence (epidemiology)
Incidence
MESH: Sex Distribution
MESH: Reference Values
MESH: Confidence Intervals
Middle Aged
Prognosis
eye
MESH: Case-Control Studies
3. Good health
Europe
Occupational Diseases
Oncology
030220 oncology & carcinogenesis
MESH: Survival Analysis
Sunlight
Female
Risk assessment
MESH: Occupational Diseases
Adult
medicine.medical_specialty
MESH: Sunlight
MESH: Melanoma
Ultraviolet Rays
malignant melanoma
Case-control Study
Risk Assessment
MESH: Prognosis
03 medical and health sciences
Age Distribution
Occupational Exposure
Confidence Intervals
Humans
Sex Distribution
MESH: Age Distribution
Aged
MESH: Humans
business.industry
Public health
Case-control study
MESH: Adult
Dermatology
Survival Analysis
eye diseases
MESH: Male
Surgery
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
Case-Control Studies
030221 ophthalmology & optometry
Etiology
MESH: Ultraviolet Rays
MESH: Uveal Neoplasms
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
sense organs
MESH: Europe
business
MESH: Female
Rare disease
Zdroj: University of Copenhagen
Cancer Causes and Control
Cancer Causes and Control, 2005, 16 (4), pp.437-47. ⟨10.1007/s10552-004-5029-6⟩
Cancer Causes and Control, Springer Verlag, 2005, 16 (4), pp.437-47. ⟨10.1007/s10552-004-5029-6⟩
ISSN: 0957-5243
1573-7225
DOI: 10.1007/s10552-004-5029-6⟩
Popis: International audience; OBJECTIVE: Uveal melanoma is a rare disease with poor prognosis and largely unknown etiology. We studied potential occupational risk factors. METHODS: A population based case-control study was undertaken during 1995-1997 in nine European countries using population and colon cancer controls with personal interviews. Occupational exposure to sunlight and artificial UV radiation was assessed with a job exposure matrix. In total, 320 uveal melanoma cases were eligible at pathology review, and 292 cases were interviewed, participation 91%. Out of 3357 population controls, 2062 were interviewed, 61%, and out of 1272 cancer controls 1094 were interviewed, 86%. RESULTS: Using population controls, occupational exposure to sunlight was not associated with an increased risk (RR=1.24, 95% CI=0.88-1.74), while an excess risk found with use of colon cancer controls was attributed to confounding factors. An excess risk in welders was restricted to the French part of the data. Cooks, RR=2.40; cleaners, RR 2.15; and laundry workers, RR=3.14, were at increased risk of uveal melanoma. CONCLUSION: Our study does overall not support an association between occupational sunlight exposure and risk of uveal melanoma. The finding of an excess risk of eye melanoma in cooks in several European countries is intriguing.
Databáze: OpenAIRE
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