Pulmonary Embolism in COVID-19 Treated with VA-ECLS and Catheter tPA
Autor: | Sinan Simsir, Steven Douedi, Daniel Kiss, Aref Obagi, Matthew D Saybolt, Daniel Flynn, Adel Aziz, Arda Akoluk, Eric J. Costanzo, Usman Mazahir |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Pulmonary and Respiratory Medicine
2019-20 coronavirus outbreak medicine.medical_specialty thrombolysis lcsh:Diseases of the circulatory (Cardiovascular) system pulmonary embolism Coronavirus disease 2019 (COVID-19) medicine.medical_treatment Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Case Report medicine.disease_cause Pandemic VA-ECMO Medicine tPA Intensive care medicine Coronavirus lcsh:RC705-779 business.industry COVID-19 Thrombolysis lcsh:Diseases of the respiratory system medicine.disease Pulmonary embolism Catheter lcsh:RC666-701 Cardiology and Cardiovascular Medicine business |
Zdroj: | Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, Vol 14 (2020) Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine |
ISSN: | 1179-5484 |
Popis: | Background: Novel coronavirus 2019 (COVID-19) has been the focus of the medical world since being declared a pandemic in March 2020. While the pathogenesis and heterogeneity of COVID-19 manifestations is still not fully understood, viral evasion of cellular immune responses and inflammatory dysregulation are believed to play essential roles in disease progression and severity. Case Presentation: We present the first case of a patient with COVID-19 with massive pulmonary embolism treated successfully with systemic thrombolysis, VA-ECLS, and bail out catheter directed thrombolysis. He was discharged from the hospital after an eventful hospital course on therapeutic anticoagulation with warfarin. Conclusions: We present the first case of a patient with COVID-19 with massive pulmonary embolism (PE) treated successfully with systemic thrombolysis, VA-ECLS and bail out catheter directed thrombolysis. In our experience catheter directed thrombolysis comes with an acceptable bleeding risk despite use of mechanical circulatory support, particularly with meticulous attention to vascular access and dose response monitoring. |
Databáze: | OpenAIRE |
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