Clinical and histological features of patients with membranoproliferative glomerulonephritis classified by immunofluorescence findings
| Autor: | Lectícia Barbosa Jorge, Denise Maria Avancini Costa Malheiros, Cristiane Bitencourt Dias, Viktoria Woronik, Leonardo de Abreu Testagrossa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty proteínas do sistema complementar Glomerulonephritis Membranoproliferative glomerulonefrite membranoproliferativa complement system proteins Fluorescent Antibody Technique Immunofluorescence lcsh:RC870-923 Membranoproliferative glomerulonephritis medicine Humans epidemiologia Retrospective Studies Gynecology medicine.diagnostic_test business.industry palavra glomerulonephritis membranoproliferative Glomerulonephritis General Medicine medicine.disease lcsh:Diseases of the genitourinary system. Urology microscopy fluorescence microscopia fluorescência Female epidemiology business |
| Zdroj: | Brazilian Journal of Nephrology v.39 n.4 2017 Jornal Brasileiro de Nefrologia Sociedade Brasileira de Nefrologia (SBN) instacron:SBN Brazilian Journal of Nephrology, Vol 39, Iss 4, Pp 447-453 |
| Popis: | Background: New classification for membranoproliferative glomerulonephritis has been proposed in the literature. The aim of this study was to compare the clinical, biochemical, etiology and renal biopsy findings of these patients grouped by immunofluorescence as proposed by the new classification. Methods: Patients with renal biopsy-proven membranoproliferative glomerulonephritis unrelated to systemic lupus erythematosus, diagnosed between 1999 and 2014. The patients were divided according to immunofluorescence: Immunoglobulin positive group, C3 positive only and negative immunofluorescence group. Results: We evaluated 92 patients, the majority of which were in the immunoglobulin positive group. Infectious diseases, hepatitis C virus and schistosomiasis, were the most frequent etiology. A negative immunofluorescence group had more vascular involvement in renal biopsy compare with others groups. Conclusions: The only difference between the groups was higher vascular involvement in renal biopsy in negative immunofluorescence group. These new classification was satisfactory for the finding of etiology in one part of the cases. |
| Databáze: | OpenAIRE |
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