Hepatitis D virus infection in the Western Brazilian Amazon - far from a vanishing disease
| Autor: | Fabiane Giovanella Borges, Wornei Silva Miranda Braga, Jorge Roberto Di Tommaso Leão, Raymundo Paraná, Eliete Pereira de Azevedo, Gildo Maia Barros Júnior, Ana Cristina de Souza Martinho, Ivo Seixas Rodrigues, Márcia da Costa Castilho |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Rural Population HBsAg viruses Disease medicine.disease_cause Risk Factors Vírus da hepatite D Epidemiology Prevalence Child Aged 80 and over biology Amazon rainforest Doença viral virus diseases Middle Aged Hepatitis B Hepatitis D Infectious Diseases Child Preschool Female Hepatitis D virus Antibody Hepatitis Delta Virus Brazil Microbiology (medical) Adult medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine Adolescent lcsh:RC955-962 Young Adult medicine Humans Hepatitis B Vaccines Hepatitis Antibodies Epidemiologia Aged Hepatitis B virus Hepatitis business.industry Infant biochemical phenomena metabolism and nutrition medicine.disease Virology Immunoglobulin G Immunology biology.protein Parasitology business |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 6, Pp 691-695 (2012) |
| ISSN: | 1678-9849 |
| Popis: | INTRODUCTION: A decline in hepatitis D virus (HDV) occurrence was described in Europe and Asia. We estimated HDV prevalence in the Brazilian Amazon following hepatitis B vaccination. METHODS: This is a cross-sectional survey of HDV measured by total antibodies to HDV (anti-HD T). RESULTS: HDV prevalence was 41.9% whiting HBsAg carries and was associated with age (PR = 1.96; 95% CI 1.12-3.42; p = 0.01), hepatitis B virus (HBV) infection (PR = 4.38; 95% CI 3.12-6.13; p < 0.001), and clinical hepatitis (PR =1.44; 95% CI 1.03-2.00; p = 0.03). Risk factors were related to HDV biology, clinical or demographic aspects such as underlying HBV infection, clinical hepatitis and age. CONCLUSIONS: Our study demonstrated that HDV infection continues to be an important health issue in the Brazilian Amazon and that the implementation of the HBV vaccination in rural Lábrea had little or no impact on the spread of HDV. This shows that HDV has not yet disappeared from HBV hyperendemic areas and reminding that it is far from being a vanishing disease in the Amazon basin. |
| Databáze: | OpenAIRE |
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