Identification of atranorin and related potential allergens in oakmoss absolute by high-performance liquid chromatography–tandem mass spectrometry using negative ion atmospheric pressure chemical ionization
| Autor: | Richard D. Hiserodt, Dennis F. H. Swijter, Cynthia J. Mussinan |
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| Rok vydání: | 2000 |
| Předmět: |
Chemical ionization
Chromatography Lichens Chemistry Organic Chemistry Absolute (perfumery) Atmospheric-pressure chemical ionization General Medicine Allergens Tandem mass spectrometry Highly selective Mass spectrometry Biochemistry High-performance liquid chromatography Mass Spectrometry Analytical Chemistry Ion Atmospheric Pressure Hydroxybenzoates Spectrophotometry Ultraviolet Chromatography High Pressure Liquid |
| Zdroj: | Journal of Chromatography A. 888:103-111 |
| ISSN: | 0021-9673 |
| DOI: | 10.1016/s0021-9673(00)00495-7 |
| Popis: | This paper describes the first high-performance liquid chromatographic-tandem mass spectrometric method for the identification of atranorin and related potential allergens in oakmoss absolute. Oakmoss absolute is ubiquitous in the fragrance industry and is a key component in many fine perfumes. However, oakmoss absolute causes an allergic response in some individuals. Research is focused toward establishing the identity of the compounds causing the allergic response so a quality controlled oakmoss with reduced allergenic potential can be prepared. Consequently a highly selective and specific analytical method is necessary to support this effort. This is not available with the existing HPLC methods using UV detection. |
| Databáze: | OpenAIRE |
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