Association of Marek’s Disease with Ea-B and Immune Response Genes in Subline and F2 Populations of the Iowa State S1 Leghorn Line
| Autor: | I. Kujdych, Susan J. Lamont, Edward M. Steadham, Arne W. Nordskog |
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| Rok vydání: | 1987 |
| Předmět: |
Male
Serotype Isoantigens Erythrocytes animal structures viruses Genes MHC Class II Major histocompatibility complex Poultry Virus Immune system Species Specificity Marek Disease Animals Blood type Rous sarcoma virus Marek's disease biology General Medicine biology.organism_classification Immunity Innate White (mutation) Immunology biology.protein Female Animal Science and Zoology Chickens |
| Zdroj: | Poultry Science. 66:571-575 |
| ISSN: | 0032-5791 |
| DOI: | 10.3382/ps.0660571 |
| Popis: | Chickens from the Iowa State S1 White Leghorn line, selected for characteristics of Ea-B serotype, humoral immune response to glutamic acid-alanine-tyrosine (Ir-GAT), and response to Rous sarcoma virus (RSV)-induced tumors, were evaluated for genetic resistance to Marek's disease (MD). In the first two trials, sublines that were triple homozygous for the three traits were challenged with MD virus. Birds of the B1B1 blood type were significantly (P less than .001) more resistant to MD than chickens of the B19B19 blood type. High responders to GAT were significantly (P less than .001) more resistant to MD virus than low responders. The RSV classification had no detectable association with MD resistance. Chickens challenged with MD virus in the third trial were an F2 population produced from inter se matings of S1 chickens heterozygous for the three traits under selection. Data from this trial confirmed increased MD resistance of chickens possessing the B1B1 blood type when associated with genes encoding high immune response to GAT. |
| Databáze: | OpenAIRE |
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