Omega-3 index and AA/EPA ratio as biomarkers of running-related injuries: An observational study in recreational runners
| Autor: | Mariano Intrieri, Stefano Righetti, Luca Mondazzi, Sergio Davinelli, Sawan Ali, Graziamaria Corbi, Giovanni Scapagnini |
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| Přispěvatelé: | Davinelli, S, Intrieri, M, Ali, S, Righetti, S, Mondazzi, L, Scapagnini, G, Corbi, G |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Population Prevalence Physical Therapy Sports Therapy and Rehabilitation Omega 3 index Running running-related injurie Internal medicine Medicine Orthopedics and Sports Medicine education Finger prick chemistry.chemical_classification education.field_of_study business.industry General Medicine polyunsaturated fatty acid Eicosapentaenoic acid AA/EPA ratio polyunsaturated fatty acids running-related injuries ω-3 index chemistry Cohort Observational study business human activities Polyunsaturated fatty acid |
| Popis: | The aim of this study was to examine the association between biomarkers of polyunsaturated fatty acids (PUFA), such as omega-3 (ω-3) index and arachidonic acid (AA; 20:4 ω-6)/eicosapentaenoic acid (EPA; 20:5ω-3) ratio (AA/EPA), and the prevalence of running-related injuries (RRI) in a cohort of recreational runners. We performed a retrospective, observational study of 275 non-elite runners (mean age: 41.20 ± 12.47 years) who were not supplemented with ω-3 fatty acids. The training characteristics and RRI were recorded over a period of 12 months through a self-reported questionnaire. Using whole blood samples collected by finger prick, PUFA were quantified by gas chromatography and ω-3 index and AA/EPA ratio measured. A total of 191 RRI cases were reported, with an injury prevalence rate of 50.9% in the overall population. The injured runners ran a significantly greater weekly distance than uninjured subjects (53.54 ± 25.27 km/week; p = 0.007). In a multivariate regression analysis, the lowest number of RRI was associated with higher values of ω-3 index (β = - 0.237; 95% CI - 0.308 to - 0.164; R2 = 0.172; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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