Does interstitial pressure oppose lung water formation?
| Autor: | Gerald S. Moss, Lawrence Krause, Lorrie A. Langdale, Charles L. Rice, Steven A. Gould |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Oncotic pressure
medicine.medical_specialty Hydrostatic pressure Statistics as Topic Pulmonary Edema Dogs Internal medicine Pressure Medicine Animals Lung business.industry Water Organ Size respiratory system Pulmonary edema medicine.disease Lung water medicine.anatomical_structure Cardiology Surgery Edema formation business Capillary membrane Interstitial pressure |
| Zdroj: | The Journal of surgical research. 34(6) |
| ISSN: | 0022-4804 |
| Popis: | The factors affecting the formation of pulmonary edema have been the subject of study and controversy for many years. In 1896, Starling [ 151 defined the relationship between the hydrostatic and oncotic forces regulating fluid flow across the capillary membrane. The protection of the lung from edema formation is necessary to maintain sufficient gas exchange to ensure normal oxygen delivery. Various “safety factors” [3, 161 have been theorized to be acting to protect the lung from increases in the extravascular lung water (EVLW). Interstitial pressure (IP) has been postulated as one of the potential safety factors [3, 161. Previous studies have found elevated IP in pulmonary edema [6, 10, 11, 12]. We asked the question, as EVLW rises during the development of pulmonary edema due to increased hydrostatic pressure, does IP rise quickly to oppose further EVLW accumulation? |
| Databáze: | OpenAIRE |
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