Healing of severe ulcerative necrobiosis lipoidica with cyclosporin

Autor: Amy Stanway, Marius Rademaker, Paul Newman
Rok vydání: 2004
Předmět:
Zdroj: Australasian Journal of Dermatology. 45:119-122
ISSN: 1440-0960
0004-8380
DOI: 10.1111/j.1440-0960.2004.00059.x
Popis: A 55-year-old woman with severe, chronic, treatment-resistant ulcerating necrobiosis lipoidica of the shins was commenced on oral cyclosporin at a dose of 2.5 mg/kg/day. Improvement started within 1 week of commencing treatment, and the lesions healed completely over 8 months. Further ulceration occurred 3 months after discontinuing cyclosporin, with improvement on reintroduction of cyclosporin. There have been four previous case reports of healing of treatment-resistant ulcerating necrobiosis lipoidica with cyclosporin.
Databáze: OpenAIRE