Efficacy of Rituximab for Refractory Pyoderma Gangrenosum-Like Ulcers in Granulomatosis With Polyangiitis Associated to Antiphospholipid Antibodies
| Autor: | Jorge L. Musuruana, Cecilia A. Costa, Javier A. Cavallasca, Julia L. Riera |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Case Report Lesion 03 medical and health sciences 0302 clinical medicine rituximab Rheumatology Refractory Rituximab therapy Female patient medicine 030212 general & internal medicine 030203 arthritis & rheumatology granulomatosis with polyangiitis biology business.industry Antiphospholipid antibodies medicine.disease Dermatology biology.protein Rituximab medicine.symptom Antibody business Granulomatosis with polyangiitis Pyoderma gangrenosum medicine.drug pyoderma gangrenosum |
| Zdroj: | Archives of Rheumatology |
| ISSN: | 2618-6500 2148-5046 |
| Popis: | Pyoderma gangrenosum (PG) is a neutrophilic dermatosis that most often presents with painful ulcerations of violaceous borders in lower limbs and/or trunk. PG treatment varies according to the severity of the lesion and may either respond to local therapies or require immunosuppressive agents. In this article, we present the case of an antiphospholipid antibody-positive 59-year-old female patient diagnosed with granulomatosis with polyangiitis who developed severe PG-like skin involvement that was responsive to rituximab therapy. |
| Databáze: | OpenAIRE |
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