Retrieval of precursors for white-type adipose conversion in brown adipose tissue
| Autor: | Rajagopal Krishnamoorthy, Malika Ouagued, C. M. Poissonnet, J Y Pello, Elisabeth Swierczewski, Yolande Aron |
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| Rok vydání: | 1988 |
| Předmět: |
medicine.medical_specialty
Adipose tissue macrophages Adipose tissue Glycerolphosphate Dehydrogenase White adipose tissue Biology Biochemistry Electron Transport Complex IV chemistry.chemical_compound Adipose Tissue Brown Internal medicine Adipocyte Brown adipose tissue medicine Animals Molecular Biology Cells Cultured PRDM16 nutritional and metabolic diseases food and beverages 3T3-L1 Cell Biology Hormones Cell Compartmentation Mitochondria Rats Lipoprotein Lipase Microscopy Electron Endocrinology medicine.anatomical_structure chemistry Cell culture lipids (amino acids peptides and proteins) Cell Division hormones hormone substitutes and hormone antagonists Research Article |
| Zdroj: | Biochemical Journal. 255:849-854 |
| ISSN: | 1470-8728 0264-6021 |
| DOI: | 10.1042/bj2550849 |
| Popis: | A cellular compartment from brown adipose tissue (BAT) of newborn rats was isolated by Percoll-density-gradient centrifugation and was shown to proliferate and to undergo adipose conversion in vitro in primary culture. The features of the effector requirement for adipose conversion as well as the differentiated morphological and biochemical phenotype are almost identical with that of a compartment designated HCF, from white adipose tissue (WAT). A possible role for these precursors from BAT and WAT in the involution of BAT into WAT, on the one hand, and in the development of brown adipose cells among typical WAT deposits, on the other, is discussed. |
| Databáze: | OpenAIRE |
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