Iodixanol is readily eliminated by hemodialysis

Autor: G. Stake, Knut Joachim Berg, B. Rolfsen
Rok vydání: 1998
Předmět:
Zdroj: Acta radiologica (Stockholm, Sweden : 1987). 39(4)
ISSN: 0284-1851
Popis: Purpose, Material and Methods, and Results: The dialyzability of the high-molecular X-ray contrast medium iodixanol was examined in an in vitro hemo-dialysis model using two different hollow fiber membranes: one high-flux (polysulfone) membrane and one intermediate-flux (cellulose triacetate) membrane. Blood flow was 200 ml/min and membrane area 1.3 m2. The dialyzer clearance of iodixanol dissolved in a mixture of leukocyte-filtered SAG-M blood and compatible citrate plasma was 134.2±3.6 ml/min for the polysulfone membrane and 113.0±3.6 ml/min for the cellulose triacetate membrane. Conclusion: Iodixanol is readily dialyzed through commercial high-flux membranes.
Databáze: OpenAIRE