Celebrating 30 years of ART in Latin America; and the 2018 report‡§

Autor: Javier Crosby, Natalia Posada, José María Mojarra, Carolina Musri, Diego Masoli, A Gustavo Martínez, Adelino Amaral Silva, Maria do Carmo Borges de Souza, Fernando Zegers-Hochschild
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Adult
Male
0301 basic medicine
safety
medicine.medical_specialty
Latin Americans
Reproductive Techniques
Assisted
medicine.medical_treatment
Multiple Birth Offspring
REDLARA Page
History
21st Century
03 medical and health sciences
0302 clinical medicine
Pregnancy
Epidemiology
Medicine
Safe system
Humans
In patient
Registries
efficacy and perinatal outcome
Double embryo transfer
Latin American Registry of ART
Retrospective Studies
030219 obstetrics & reproductive medicine
Assisted reproductive technology
business.industry
Infant
Newborn
Pregnancy Outcome
Obstetrics and Gynecology
History
20th Century
30 years' trend analysis
Embryo transfer
Treatment Outcome
030104 developmental biology
Latin America
Reproductive Medicine
Infertility
Female
Pregnancy
Multiple
business
Live birth
Live Birth
Developmental Biology
Demography
Zdroj: JBRA Assisted Reproduction
ISSN: 1518-0557
1517-5693
Popis: Research question What are the trends in patient characteristics, effectiveness and safety of assisted reproductive technology (ART) performed in Latin America over the past three decades, as well as the detailed outcomes of procedures initiated in 2018? Design Retrospective collection of multinational data including epidemiology and outcomes of ART performed between 1990 and 2018. Results Over these 30 years we report 955,117 initiated cycles, 191,191 deliveries and 238,045 live births. In 1990, 66.5% of women were ≤34 years and 8.7% ≥40 years; in 2018, 26.4% of women were ≤34 years and 32.0% were ≥40 years. In 1990, 60.4% of transfers included ≥3 embryos, falling to 13.5% in 2018, and single embryo transfer (SET) increased from 13.8% to 30.4% between 1990 and 2018. Delivery rate per fresh transfer increased from approximately 17% in the 1990s to 25% in 2018, with a meaningful drop in high-order multiples, from 5–9% in the 1990s to 0.4% in 2018. This drop is associated with increasing use of frozen embryo transfer (FET) (57% in 2018) compared with 10% in 2000. In 2018, delivery rate in FET was 28.3%, reaching 31.2% in freeze-all cycles; and the cumulative live birth rate (fresh + FET) was 41.9%. Elective SET also increased, from 0.9% in 2010 to 10% in 2018. The delivery rate in elective SET (31.7%) was only 5.4% lower than elective double embryo transfer (DET) (37.1%); however, multiple births increased from 2.1% to 25.5% twins and 0.4% triplets in elective DET. Conclusion The Latin American Registry of Assisted Reproduction (RLA) celebrates 30 years of voluntary reporting from a total of nearly 200 centres in 15 countries. This South–South Cooperation network has proven to be an efficient and safe system for technological transfer and regional growth.
Databáze: OpenAIRE
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