A multicenter study of three-dimensional echocardiographic evaluation of normal pediatric left ventricular volumes and function
| Autor: | Pei-Ni Jone, Tim Colen, Benjamin H. Goot, Gerald R. Marx, Zhaoxing Pan, Alessandra M. Ferraro, Nee S. Khoo, David M. Harrild, Lisa Le, Sachie Shigemitsu, Anitha Parthiban |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adolescent
Intraclass correlation Heart Ventricles Left Echocardiography Three-Dimensional 030204 cardiovascular system & hematology left ventricular volume Pediatrics Ventricular Function Left 030218 nuclear medicine & medical imaging 03 medical and health sciences left ventricular function 0302 clinical medicine Cardiac magnetic resonance imaging medicine three-dimensional echocardiography Humans Ventricular Function Radiology Nuclear Medicine and imaging normal data Child Child Preschool Infant Infant Newborn Reproducibility of Results Stroke Volume Preschool Body surface area Ejection fraction medicine.diagnostic_test business.industry Three dimensional echocardiography Stroke volume Repeatability Newborn Multicenter study Echocardiography Three-Dimensional Cardiology and Cardiovascular Medicine business Nuclear medicine |
| Popis: | Background: Three-dimensional echocardiography (3DE) evaluation of left ventricular (LV) volume and function in pediatrics compares favorably with cardiac magnetic resonance imaging. The aim of this study was to establish from a multicenter, normal pediatric z-score values of 3DE left ventricular volumes and function. Methods: Six hundred and ninety-eight healthy children (ages 0 to 18 years) were recruited from five centers. LV 3DE was acquired from the 4-chamber view. A vendor independent software analyzed end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) using semi-automated quantification. Body surface area (BSA) based z-scores were generated. Intraobserver and interobserver variability were calculated using intraclass correlation (ICC) and repeatability coefficient (RC). Results: Z-scores were generated for ESV, EDV, and SV. The ICC for intraobserver variability for EDV, ESV, and SV were 0.99, 0.99, and 0.99 respectively. The ICC for interobserver variability for EDV, ESV, and SV were 0.98, 0.94, and 0.98 respectively. The RC for intraobserver and interobserver variability for LV EF was 4.39% (95% CI: 3.01, 5.59) and interobserver was 7.08% (95%CI: 5.51, 8.42). Conclusions: We report pediatric Z-scores for normal LV volumes using the semi-automated method from five centers, enhancing its generalizability. 3DE evaluation of LV volumes and EF in pediatric patients is highly reproducible. |
| Databáze: | OpenAIRE |
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