[Pathogenesis of beta-lactam-resistant Haemophilus influenzae isolated from sputum]
| Autor: | Shigeki Odagiri, Takashi Ogura, Toshiaki Tomioka, Yuji Watanuki, Hiroshi Takahashi |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Microbial Sensitivity Tests medicine.disease_cause beta-Lactam Resistance beta-Lactamases Haemophilus influenzae Microbiology Pathogenesis Ampicillin medicine Humans Pathogen Respiratory Tract Infections Aged Respiratory tract infections biology business.industry Sputum General Medicine Middle Aged biology.organism_classification medicine.anatomical_structure Female medicine.symptom business Bacteria Ampicillin Resistance Respiratory tract medicine.drug |
| Zdroj: | Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 78(10) |
| ISSN: | 0387-5911 |
| Popis: | Haemophlus influenzae persists in the respiratory tract and sometimes causes respiratory tract infections. To evaluate the pathogenesis of beta-lactam-resistant Haemophilus influenzae, we classified 193 Haemophilus influenzae strains isolated from sputum of patients with respiratory tract disease in 24 beta-lactamase positive (BLP) strains, 65 beta-lactamase negative ampicillin resistant (BLNAR) strains and 104 beta-lactamase negative ampicillin sensitive (BLNAS) strains and reviewed the pathogenesis of the strains. The pathogenesis of the strains was evaluated as definite pathogen, presumptive pathogen, colonization and contamination. It was judged to be the definite pathogen that many bacteria isolated from high quality sputum of the patients with respiratory tract infections. Presumptive pathogen was considered to be the bacteria provided from the patient with respiratory infections when the quality of the sputum or quantity of bacteria did not satisfy superscription basis. We considered the bacteria to be colonization or contamination isolated from patients without infections. The breakdown of definite pathogen/presumptive pathogen/colonization/contamination in each by groups was BLP (8/4/8/4), BLNAR (26/14/15/10), BLNAS (36/20/31/17). The ratio of definite or presumptive pathogen was 50% in BLP, 62% in BLNAR and 54% in BLNAS and the significant difference was not recognized in these. Pathogenesis of beta-lactam-resistant Haemophilus influenzae is estimated to be equal with beta-lactam-sensitive Haemophilus influenzae. |
| Databáze: | OpenAIRE |
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