HYPERVENTILATION AND HYPOVOLÆMIA DURING EXERCISE AT ALTITUDE
| Autor: | P.W. Straub, M. Spiegel, A.A. Bühlmann |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Male
Strenuous exercise Physical Exertion Blood volume Sports Medicine Altitude Hyperventilation medicine Humans Hypoxia Oxygen pressure Blood Volume Blood Volume Determination business.industry Hemodynamics General Medicine Water-Electrolyte Balance Hematocrit Spirometry Anesthesia Breathing Moderate hypoxia Anuria medicine.symptom business Blood Chemical Analysis |
| Zdroj: | The Lancet. 295:1021-1022 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(70)91150-5 |
| Popis: | The observation of a prolonged period Summary of anuria after the physical breakdown of one of the Swiss oarsmen at the 1968 Olympic Games in Mexico City led to the suspicion that hypovolaemia might have played a pathogenetic role. Blood-volume S a O 2 , pH, P a CO 2 , blood-lactate, serum electrolytes, arterial blood-pressure, and pulse-rate, were measured in fourteen oarsmen before, during, and after strenuous exercise on a bicycle ergometer both at normal and reduced oxygen pressure. Exercise at a moderate hypoxia corresponding to an altitude of 2000-3000 m. led to the same decrease of blood-volume as observed at normal P I O 2 , but was associated with a higher lactate concentration, higher pulse-rate, and somewhat higher blood-pressure. Spontaneous or voluntary hyperventilation during exercise at a reduced P I O 2 , however, resulted in an 18% greater decrease in blood volume than observed with normal ventilation. Despite less striking hypoxaemia, the lactate concentration and pulse-rate were higher and the mean arterial blood-pressure slightly lower. These results suggest that the frequent breakdowns of athletes during the 1968 Olympics were due, at least in part, to hypovolaemia accentuated by hyperventilation. |
| Databáze: | OpenAIRE |
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