Association of residential greenness and incident depression: Investigating the mediation and interaction effects of particulate matter

Autor: Xinhan, Zhang, Fang, Wei, Zhebin, Yu, Fanjia, Guo, Jianbing, Wang, Mingjuan, Jin, Liming, Shui, Hongbo, Lin, Mengling, Tang, Kun, Chen
Rok vydání: 2022
Předmět:
Zdroj: Science of The Total Environment. 811:152372
ISSN: 0048-9697
Popis: Growing evidence has linked residential greenness to depression, the results from prospective cohort study are still limited. And it remains unclear whether particulate matter (PM) modify, mediate, or interact the greenness-depression relationship.We collected data from Yinzhou Cohort(N = 47,516) which was recruited between June 2015 and December 2017. Depression cases before April 2020 were ascertained from local Health Information System covered all residents' health care records. Residential greenness (the Normalized Difference Vegetation Index, NDVI, and the Enhanced Vegetation Index, EVI) and PM (particulate matters with diameters≤2.5 μm, PMDuring the 99,556 person-years of follow-up, 1043 incident depression cases occurred. In single exposure models, residential greenness was inversely associated with depression incidence (e.g. Hazard Ratio (HR) = 0.86, 95% confidence interval (CI): 0.79, 0.94 for per interquartile range (IQR) increase NDVI 250 m). The protective association between greenness was attenuated after introducing PMIn this longitudinal cohort study, residents living in greener neighborhoods had a lower risk of depression incidence and the benefits were interacted and partly mediated by PM. Improvement in residential greenness could be an actionable and planning intervention to prevent depression.
Databáze: OpenAIRE