L-asparaginase Produced from Endophytes: Production, Optimization and Anticancer Activities

Autor:	Yap, Ling Sze
Rok vydání:	2021
Předmět:	Bioprocessing bioproduction and bioproducts Biocatalysis and enzyme technology Medical biotechnology not elsewhere classified Enzymes
DOI:	10.26180/16780705
Popis:	L-asparaginase is an anticancer drug used to treat acute lymphoblastic leukemia. The commercial available L-asparaginase derived from bacteria has reported to induce several life-threatening side effects and irreversible complications. This thesis examines the utilization of endophytic fungi isolated from medicinal plants as an alternative source of L-asparaginase. It demonstrates the ability of endophytic fungi to produce L-asparaginase, factors affecting L-asparaginase production, purification process and anticancer effect of fungal-derived L-asparaginase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c9e842d2977fe164f6444f95a12b95 Zobrazit plný text záznamu