Effect of Comorbidities on Inflammatory Bowel Disease-Related Colorectal Cancer: A Nationwide Inpatient Review
| Autor: | Arnold N Forlemu, Raissa Nana Sede Mbakop, Shehroz Aslam, Zaid Ansari, Indu Srinivasan, Keng-Yu Chuang |
|---|---|
| Přispěvatelé: | University of Nebraska Medical Center, University of Nebraska System, Université de Rennes (UR), CHU Pontchaillou [Rennes], Creighton University |
| Rok vydání: | 2022 |
| Předmět: |
General Engineering
cancer surveillance crohn?s disease [SDV.CAN]Life Sciences [q-bio]/Cancer [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie liver disease comorbidities colorectal neoplasia ulcerative colitis |
| Zdroj: | Cureus Journal of Medical Science Cureus Journal of Medical Science, 2022, 14 (8), pp.e27599. ⟨10.7759/cureus.27599⟩ |
| ISSN: | 2168-8184 |
| Popis: | International audience; Introduction: The risk of inflammatory bowel disease-associated colorectal cancer (IBD-CRC) is known to increase with primary sclerosing cholangitis (PSC) and a family history of CRC. However, the impact of comorbidities such as liver disease, obesity, diabetes, chronic lung, heart, and renal disease, and psychiatric illness on the risk of IBD-CRC remains unclear. We evaluated the effect of these comorbidities on the risk of IBD-CRC.Methods: A retrospective review from 2009 to 2014 was conducted using the National Inpatient Sample data for adults 18 years and older. Patients with IBD (360,892), of whom 2,831 had CRC were identified using the International Classification of Diseases, Ninth Revision codes (ICD-9). Data on comorbidities were also obtained. Adjusted odds ratios (aOR) and confidence intervals (CI) were computed via logistic regression to evaluate the effect of comorbidities on the risk of IBD-CRC; the p-value was set at |
| Databáze: | OpenAIRE |
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