Artery Stenosis of the Renal Graft: Experience of a Center of Northeastern Brazil
| Autor: | Elizabeth De Francesco Daher, Sônia Leite da Silva, A.G. Fernandes, João Batista Gadelha de Cerqueira, S. Souza, L.C.d.O. Santos, Paula Frassinetti Castelo Branco Camurça Fernandes, Wilson Mendes Barroso, Claudia Maria Costa de Oliveira, Jarinne Camilo Landim Nasserala, Silvana Cristina de Albuquerque Andrade |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Population Urology Renal Artery Obstruction Renal function Blood Pressure 030204 cardiovascular system & hematology 030230 surgery Kidney 03 medical and health sciences Renal Artery 0302 clinical medicine Risk Factors Transplante de Rim medicine.artery Prevalence medicine Humans Renal Insufficiency Kidney surgery Renal artery education Antihypertensive Agents Retrospective Studies Transplantation education.field_of_study business.industry Graft Occlusion Vascular Odds ratio Middle Aged Kidney Transplantation Surgery Treatment Outcome medicine.anatomical_structure Blood pressure Case-Control Studies Female Transplant renal business Brazil Artery |
| Zdroj: | Repositório Institucional da Universidade Federal do Ceará (UFC) Universidade Federal do Ceará (UFC) instacron:UFC |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2015.11.004 |
| Popis: | Background Transplant renal artery stenosis (TRAS), the most common vascular complication after transplant (Tx), leads to resistant hypertension, impaired renal function, and even loss of the graft. The purpose of the study was to investigate the prevalence and factors associated with TRAS in northeastern Brazil. Methods The study was conducted as a retrospective case-control study in a population of Tx recipients in a renal Tx center in northeastern Brazil. Demographic and clinical characteristics of the recipients and donors, data related to the surgery, laboratory data, and number of anti-hypertensive drugs were assessed. Statistical analysis was performed with the use of SPSS 17.0. Results A total of 494 of 529 recipients were assessed, of which 24 had TRAS. The prevalence of TRAS was 4.8%. Twelve patients (50%) were men with a mean age of 46.7 ± 13.5 years. The mean time of diagnosis was 89.9 days after Tx. The risk factors associated with TRAS were number of anti-hypertensive drugs ≥2 (odds ratio, 17.0; confidence interval, 4.1 to 70.4; P = .001) and grafting with 2 or more arteries (odds ratio, 8.9; confidence interval, 1.4 to 56.6; P = .021). There was a significant reduction in mean systolic blood pressure (147.1 ± 23.7 to 127.8 ± 15.2 mm Hg, P = .001) and diastolic blood pressure (86.6 ± 13.0 to 77.6 ± 9.4 mm Hg, P = .001) after TRAS repair and in serum creatinine (2.8 ± 2.4 to 1.9 ± 1.8 mg/dL, P = .04). Conclusions Grafts with 2 or more arteries are associated with TRAS, as well as patients who use a higher number of anti-hypertensive drugs. TRAS repair was associated with improved blood pressure control and renal function. |
| Databáze: | OpenAIRE |
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